Disc degeneration repair
Degenerative Disc Disease
Nearly everyone shows some signs of wear and tear on the spinal discs as they age. Not everyone, however, will have symptoms described as degenerative disc disease. Not actually a disease, degenerative disc disease refers to a condition in which pain is caused from a damaged disc. A wide range of symptoms and severity is associated with this condition.
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Degenerative Disc Disease, when is surgery needed?
More than 65 million Americans suffer from low back pain annually. By age 50, 85% of the population will show evidence of disc degeneration. Luckily, most will have no symptoms.
Degeneration of the intervertebral disc, which is often called degenerative disc disease (DDD) or osteoarthritis of the spine, is a common disorder of the lower spine. Disc degeneration can lead to disorders such as lumbar spinal stenosis (narrowing of the spinal canal that houses the spinal cord and nerve roots), spondylolisthesis (forward slippage of the disc and vertebra), and retrolisthesis (backward slippage of the disc and vertebra) (Fig. 1). Actually, DDD is not a disease but, rather, a degenerative condition that can be painful and can greatly affect your quality of life. Disc degeneration is a normal part of aging and is generally not a problem by itself. However, when bone spurs grow adjacent to the discs, they can pinch or put pressure on the nearby nerve roots or spinal canal, and pain can occur.
Causes
Aging is the most common cause of disc degeneration. As the body ages, the discs in the spine dehydrate, or dry out, and lose their ability to act as shock absorbers between the vertebra. The bones and ligaments that make up the spine also become less flexible and thicken. Unlike muscles, there is minimal blood supply to the discs so they lack the ability to heal or repair themselves.
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Degenerative disc disease
Degeneration of the intervertebral disc, often called "degenerative disc disease" (DDD) of the spine, is a condition that can be painful and can greatly affect the quality of one's life. While disc degeneration is a normal part of aging and for most people is not a problem, for certain individuals a degenerated disc can cause severe constant chronic pain.
Source: Wikipedia - Causes, symptoms, treatment options of Degenerative disc disease ...
Single Injection of GDF-5 May Repair Degenerated Discs
A single injection of recombinant human growth and differentiation factor (GDF-5) may induce recovery of intravertebral disc height (IVD), according to a study of New Zealand white rabbits presented Sunday at the annual meeting of the Orthopaedic Research Society in Chicago, Illinois.1 A member of the bone morphogenic protein (BMP) family, GDF-5 is important for the development of the musculoskeletal system. Injections of this protein target the earliest stage of disc degeneration when cells are both viable and functional.
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